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Petition to Establish the Advanced Approval Pathway for Longevity Medicines (AAPLM)

The Advanced Approval Pathway for Longevity Medicines aims to incentivize the development of longevity therapies by aligning economic benefits with public health improvements.

The Issue

The Advanced Approval Pathway for Longevity Medicines (AAPLM) aims to incentivize the development of longevity therapies by aligning economic benefits with public health improvements. This pathway includes three key provisions: (1) a faster approval process for longevity medicine, (2) transferable Priority Review Vouchers (PRVs), and (3) patent extensions granted on a per-indication basis. These incentives allow companies to bring therapies to market more quickly, improve financial stability through voucher sales, and increase asset value for investors through patent extensions, supporting broader, longer-term clinical development and trials for age-related diseases.

By signing this petition, you support the creation of the Advanced Approval Pathway for Longevity Medicines (AAPLM) that will help companies accelerate their developments and approvals of therapies targeting aging and age-related multi-morbidities, expanding access to innovative treatments. Together, we can advance public health, enhance quality of life, and drive economic growth by fostering groundbreaking solutions to the challenges of aging.

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Carlo Tanratore

Georgetown University

Dr. Tornatore is the Regional Chief of Neurology for MedStar Health and Chairman and Neurologist-in-Chief in the Department of Neurology at MedStar Georgetown University Hospital. He is also the Executive Director of the Multiple Sclerosis Patient Centered Specialty Practice­ MedStar Georgetown and Professor and Chairman in the Department of Neurology at Georgetown University Medical Center. Dr. Tornatore received his undergraduate degree in neurobiology from Cornell University and then attended Georgetown University School of Medicine where he received his medical degree. Following a Neurology Residency at Georgetown University Hospital, he was a post-doctoral fellow at the National Institute of Neurologic Disorders and Stroke at the National Institutes of Health. Dr. Tornatore has published extensively in the areas of neuroimmunology, neurovirology and Multiple Sclerosis and is currently involved in over 15 clinical trials for the treatment of Multiple Sclerosis. He has won multiple awards in the areas of medical student teaching, patient care and scholarly research.